Carte VILSMEIER-HAACK REAGENT AIDED SYNTHESIS Radhey Mohan Singh

VILSMEIER-HAACK REAGENT AIDED SYNTHESIS

QUINOLINE BASED FUSED HETEROCYCLIC

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Legare: Carte broșată
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Vilsmeier-Haack reaction has been recognised as one of the most relevant tool both of industrial and...

Informații despre carte

Limbă
engleză
Legare
Carte - Carte broșată
Publicat
2009
Pagini
124
EAN
9783639187984
Enbook ID
06826933
Greutate
205
Dimensiuni
149 x 218 x 13

Descriere completă

Vilsmeier-Haack reaction has been recognised as one of the most relevant tool both of industrial and academic importance. The reagent undergoes different courses of reactions, namely formylation, acylhaloaddition, cyclization, ring annulation and dehydroxylation. The work entitled, Vilsmeier-Haack Reagent Aided Synthesis and Quinoline based Fused Heterocyclic Compounds , deals the brief survey on the applications of Vilsmeier-Haack reagent on the organic compounds containing different functional groups and discussed the synthesis of 2-chloro-3- formylquinolines and 2-chloro-3-formylbenzo[f] quinolines, respectively from the reaction of acetanilides and N-acetyl-2-naphthylamine using Vilsmeier-Haack reagent.Further, the various chemical evidences are described to establish the structure of the compounds such as the conversion of the 3-formyl group into the anils, oximes, hydrazones, semicarbazones, nitriles, esters, acetals, homoallyl and homopropargyl alcohols and substitution at the 2-chloro group by sulphur, oxygen and nitrogen nucleophiles.

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