Towards a New Neuromorphology

Name: Towards a New Neuromorphology
Brand: Springer International Publishing AG
SKU: 9783319256924
Price: 1203.4 RON
Availability: InStock

Autor: Rudolf Nieuwenhuys, Luis Puelles

Limbă:

Legare: Copertă tare

Editura: Springer International Publishing AG

Disponibilitate: În depozitul extern

Expediem în 10-13 zile

1 203.40 lei

This book demonstrates that the systematic study of gene expression patterns in embryonic and adult...

Informații despre carte

Autor

Rudolf Nieuwenhuys, Luis Puelles

Limbă

engleză

Legare

Carte - Copertă tare

Publicat

2015

Pagini

344

EAN

9783319256924

ISBN

3319256920

Enbook ID

09542217

Editura

Springer International Publishing AG

Greutate

1150

Dimensiuni

288 x 217 x 24

Descriere completă

This book demonstrates that the systematic study of gene expression patterns in embryonic and adult brains, in combination with selected data from earlier studies, can pave the way for a new neuromorphology, the most salient features of which may be summarized as follows: (1) Causal analysis of molecular patterning at neural plate and early neural tube stages has shown that the CNS is essentially organized into transverse neural segments or neuromeres and longitudinal zones which follow the curved axis of the brain. (2) The FMUs initially represent thin neuroepithelial fields; in the course of further development they are transformed into three-dimensional radial units, extending from the ventricular surface to the meningeal surface of the brain. (3) The principal histogenetic processes, including cellular proliferation, cell migration and differentiation, essentially take place within the confines of these radial units, controlled by characteristic sets of developmental regulatory genes. (4) Although most developing neurons migrate radially and settle within their own FMU, at many locations neuroblasts leave the FMU where they were produced and migrate tangentially to other nearby or remote territories, colonizing parts of foreign FMUs. (5) Many structural complexes in the adult brain, including the cerebral and cerebellar cortices, are the products of radial and tangential intermingling of migrated cell contingents.§(6) By using appropriate molecular markers, all neuron types in the adult CNS can be traced back to a specific progenitor zone within a specific FMU, and the progeny of any FMU can be traced to their final positions with the help of selective labeling approaches. (7) Early outgrowing axons form bundles, which tend to pass close to the border zones of the radial units. By means of their molecularly diversely tuned growth cones, these extending axons decide how to behave at each boundary they encounter, sometimes even reorienting at right angles. Collectively these early axonal bundles form a checkerboard-like scaffold, which accentuates the molecular regionalization of the CNS and leads to the formation of topographically ordered synaptic fields.§§The book covers all of these aspects in detail, providing a morphologic model (blueprint) that highlights the natural coordinates of CNS structure resulting from the conserved molecularly controlled shaping phenomena within morphogenetic fields.§§

S-ar putea să te intereseze

Clienții care au cumpărat această carte au mai cumpărat și

Cele mai căutate

Categories

Authors

Publishers

Produse

Produse

Cele mai căutate

Categories

Authors

Publishers

Produse

Produse

Towards a New Neuromorphology

Informații despre carte

Descriere completă

S-ar putea să te intereseze

Pop Sculpture

The Art Of Seduction

Classics of Buddhism and Zen, Volume One

Canoeing the Mountain gifts from the waters

Honda Accord & Crosstour (03-14)

Final Takedown

Sink 'Em All

No Bullsh*t Leadership

The Story Of My Life

Frank Miller's Sin City Volume 3

Clienții care au cumpărat această carte au mai cumpărat și

Scapa Flow

Le carnet de Thibault - Lignes, 96p, A5 - Ronds Orange Gris Violet

Magic the Gathering Reality Fracture Commander Deck Multiverse Reforged Assortment (4) english