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Carte Mitotic Exit Network Fernando Monje-Casas

Mitotic Exit Network

Methods and Protocols

Autor: Fernando Monje-Casas, Ethel Queralt
Limbă: engleză
Legare: Carte broșată
Editura: Humana Press Inc.
Disponibilitate: În depozitul extern
Expediem în 5-8 zile
592.90 lei
This detailed book collects the main methodologies used for the analysis of the activity, localizati...

Informații despre carte

Autor
Fernando Monje-Casas, Ethel Queralt
Limbă
engleză
Legare
Carte - Carte broșată
Publicat
2018
Pagini
281
EAN
9781493982202
Enbook ID
20091880
Editura
Humana Press Inc.
Greutate
5525
Dimensiuni
178 x 254 x 16

Descriere completă

This detailed book collects the main methodologies used for the analysis of the activity, localization, and regulation of the components of the Mitotic Exit Network (MEN) pathway during mitotic exit in Saccharomyces cerevisiae , as well as for the evaluation of the roles of these proteins in other cellular processes, such as the condensation of the rDNA, the functionality of the mitotic checkpoints, and cytokinesis. Budding yeast serves as an ideal model system for dissecting the mechanisms that regulate cell cycle progression and providing new insights into the molecular basis of cell cycle control and, thus, into the origin of diseases that arise as a consequence of problems during cell division. Therefore, although this volume concentrates on Saccharomyces cerevisiae as a model, it also details the implications that the research about the MEN have on our understanding of the mitotic exit process in higher eukaryotes. Written for the highly successful Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and practical, The Mitotic Exit Network: Methods and Protocols will be a valuable reference for cellular and molecular biologists and biochemists as well as for all scientists interested in the study of the regulation of mitotic exit using budding yeast as a model organism.

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