The CD38 molecule

Name: The CD38 molecule
Brand: LAP Lambert Academic Publishing
SKU: 9786138339779
Price: 139.49 RON
Availability: InStock

Autor: Ahlem Mokrane

Limbă:

Legare: Carte broșată

Editura: LAP Lambert Academic Publishing

Disponibilitate: În depozitul extern

Expediem în 8-11 zile

139.49 lei

CD38 is a transmembrane glycoprotein type II, which is expressed on normal hematopoietic cells and i...

Informații despre carte

Autor

Ahlem Mokrane

Limbă

engleză

Legare

Carte - Carte broșată

Publicat

2018

Pagini

EAN

9786138339779

Enbook ID

19185748

Editura

LAP Lambert Academic Publishing

Greutate

143

Dimensiuni

150 x 220 x 5

Descriere completă

CD38 is a transmembrane glycoprotein type II, which is expressed on normal hematopoietic cells and in non-hematopoietic tissues. Notably, CD38 is highly expressed in multiple myeloma, chronic lymphocytic leukemia, and other diseases. CD38 plays several roles, including ectoenzyme, receptor, adhesion molecule, and is involved in signal transduction. The cytotoxic mechanisms of daratumumab, which is considered a new high affinity human therapeutic mAb against a single CD38 epitope. CD38 represents a promising target for mAb-based immunotherapy, which has already and will continue to transform the treatment landscape into diseases, including multiple myeloma.

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