Structural Alignment

Name: Structural Alignment
Brand: VDM Verlag
SKU: 9783639279368
Price: 253.86 RON
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A Graph-Theoretic Approach

Autor: Layal Kazma

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Editura: VDM Verlag

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Structural alignment is the process of finding similarities between a pair of proteins based on thei...

Informații despre carte

Autor

Layal Kazma

Limbă

engleză

Legare

Carte - Carte broșată

Publicat

2011

Pagini

EAN

9783639279368

ISBN

3639279360

Enbook ID

06835132

Editura

VDM Verlag

Greutate

127

Dimensiuni

152 x 229 x 5

Descriere completă

Structural alignment is the process of finding similarities between a pair of proteins based on their three-dimensional shape. Accurate detection of such similarities could reveal evolutionary relationships and predict the functions of different proteins. Despite the existing algorithms, the protein structure alignment problem is not completely solved. In this work a graph-theoretic approach is considered, which consists of representing tertiary protein structures as labeled graphs, and interpreting the structural alignment problem as a particular case of the Maximum Common Subgraph (MCS) problem. Our algorithm was then implemented under parallel platforms using a combination of threads and message passing techniques. Experiments were performed on a set of proteins selected randomly from the Protein Data Bank. The experiments proved the time- efficiency and accuracy of our method when compared to several other algorithms.

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Structural Alignment

A Graph-Theoretic Approach

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Descriere completă

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