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Steroid Receptor Methods

Name: Steroid Receptor Methods
Brand: Humana Press Inc.
SKU: 9781617371707
Price: 574.75 RON
Availability: InStock

Protocols and Assays

Autor: Benjamin A. Lieberman

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Legare: Carte broșată

Editura: Humana Press Inc.

Disponibilitate: În depozitul extern în cantități mici

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574.75 lei

A distinguished team of principal investigators and their associates describe in step-by-step detail...

Informații despre carte

Autor

Benjamin A. Lieberman

Limbă

engleză

Legare

Carte - Carte broșată

Publicat

2010

Pagini

381

EAN

9781617371707

ISBN

161737170X

Enbook ID

01431902

Editura

Humana Press Inc.

Greutate

581

Dimensiuni

152 x 229 x 22

Descriere completă

A distinguished team of principal investigators and their associates describe in step-by-step detail a cross-section of the latest research techniques available for studying the endocrine system. As a basis for sophisticated biochemical analysis of receptor properties, the contributors provide methods for the production and purification of a variety of receptors, including progesterone, glucocorticoid, and androgen. Other protocols allow the reader to experiment with DNA binding characteristics, hormone binding assays, and the use of combinatorial chemistry for drug discovery. A series of novel methods utilizing the latest advances in immunochemistry, yeast two-hybrid screening, and fluorescence are included for the detection and analysis of a variety of cellular proteins that influence steroid receptor effectiveness.Research into steroid receptor biology holds great promise for the treatment of cancer and endocrine disorders and for elucidating the fundamental biological mechanisms of gene expression. In Steroid Receptor Methods: Protocols and Assays, a distinguished team of principal investigators and their associates describe in step-by-step detail a cross-section of the latest research techniques available for studying the endocrine system. As a basis for sophisticated biochemical analysis of receptor properties, the contributors provide methods for the production and purification of a variety of receptors, including progesterone, glucocorticoid, and androgen. Other protocols allow the reader to experiment with DNA-binding characteristics and hormone-binding assays and with the use of combinatorial chemistry for drug discovery. A series of novel methods utilizing the latest advances in immunochemistry, yeast two-hybrid screening, and fluorescence are included for the detection and analysis of a variety of cellular proteins that influence steroid receptor effectiveness. Finally, a discussion by example presents the most current bioinformatics tools and analytical techniques.§Timely and highly accessible, Steroid Receptor Methods: Protocols and Assays provides biochemists and molecular biologists studying endocrine systems with a full range of the powerful tools needed for elucidating protein interactions with receptors and DNA, as well as for drug discovery.