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Carte Specificity, Function, and Development of NK Cells Marco Colonna

Specificity, Function, and Development of NK Cells

NK Cells: The Effector Arm of Innate Immunity

Autor: Marco Colonna, Klas Kärre
Limbă: engleză
Legare: Carte broșată
Editura: Springer-Verlag Berlin and Heidelberg GmbH & Co. KG
Disponibilitate: În depozitul extern
Expediem în 8-11 zile
550.75 lei
Our understanding of the function of natural killer (NK) cells has dramatically changed in recent ye...

Informații despre carte

Autor
Marco Colonna, Klas Kärre
Limbă
engleză
Legare
Carte - Carte broșată
Publicat
2012
Pagini
248
EAN
9783642468612
ISBN
3642468616
Enbook ID
07110297
Editura
Springer-Verlag Berlin and Heidelberg GmbH & Co. KG
Greutate
406
Dimensiuni
155 x 235 x 15

Descriere completă

Our understanding of the function of natural killer (NK) cells has dramatically changed in recent years. The discovery of NK receptors specific for MHC class I molecules, and the study of the role of co-stimulatory and adhesion molecules have led to an understanding of how NK cells recognize tumor and virally infected cells that have lost expression of MHC class I molecules or have altered distribution of normal cell surface molecules. Such recognition events lead to intracellular signals which can be either stimulatory or inhibitory. This book provides an insight into how NK cells develop, how they learn to distinguish altered cells from normal cells, and into their biological role in controlling infections and tumors.

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