Solid-Phase Synthesis and Combinatorial Technologies

Autor: Pierfausto Seneci

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Legare: Copertă tare

Editura: John Wiley & Sons Inc

Disponibilitate: În depozitul extern în cantități mici

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A unique, integrated look at solid-phase synthesis and advances in combinatorial chemistry and techn...

Informații despre carte

Autor

Pierfausto Seneci

Limbă

engleză

Legare

Carte - Copertă tare

Publicat

2000

Pagini

656

EAN

9780471331957

ISBN

0471331953

Enbook ID

04889862

Editura

John Wiley & Sons Inc

Greutate

1024

Dimensiuni

162 x 239 x 35

Descriere completă

A unique, integrated look at solid-phase synthesis and advances in combinatorial chemistry and technologies The last decade has seen a rapid expansion in combinatorial technologies, a field where chemistry disciplines intersect with automation, statistics, and information science, as well as certain biological disciplines. Reflecting these multidisciplinary trends, this new work provides a comprehensive overview of the most important aspects of solid-phase synthesis (SPS), combinatorial chemistry, and related combinatorial technologies. It clearly demonstrates how SPS and combinatorial chemistry have extended their application from the pharmaceutical arena to new areas, including biotechnology, material sciences, catalysis, and agrochemical industries, and explores in detail strategies for planning, designing, preparing, and testing of combinatorial libraries in various disciplines. Designed to meet the needs of both experienced combinatorial chemists and newcomers to the field, Solid-Phase Synthesis and Combinatorial Technologies: Surveys the most recent developments in SPS and combinatorial chemistry Explains the entire process, from determining the need for a library to the details necessary for synthesis of the library Discusses choice of format, size, and the rationale behind the design of each synthetic step Surveys the analytical techniques and the purification methods used to characterize and purify combinatorial libraries Employs a large number of examples to illustrate important concepts Includes problems geared toward applying acquired knowledge and designing the steps to SPS/library synthesis Describes the quality control and activity screening of combinatorial libraries for various applications Features a detailed bibliography of more than 1,700 relevant sources

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Solid-Phase Synthesis and Combinatorial Technologies

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