Selective Estrogen Receptor Modulators

Name: Selective Estrogen Receptor Modulators
Brand: Humana Press Inc.
SKU: 9781468496659
Price: 634.14 RON
Availability: InStock

Research and Clinical Applications

Autor: Andrea Manni, Michael Verderame

Limbă:

Legare: Carte broșată

Editura: Humana Press Inc.

Disponibilitate: În depozitul extern în cantități mici

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634.14 lei

Experimental and clinical researchers from a wide range of disciplines present a wealth of fresh sci...

Informații despre carte

Autor

Andrea Manni, Michael Verderame

Limbă

engleză

Legare

Carte - Carte broșată

Publicat

2012

Pagini

374

EAN

9781468496659

ISBN

1468496654

Enbook ID

02643780

Editura

Humana Press Inc.

Greutate

728

Dimensiuni

178 x 254 x 21

Descriere completă

Experimental and clinical researchers from a wide range of disciplines present a wealth of fresh scientific information on the biochemistry, molecular biology, pharmacology, and clinical activity of SERMs. The basic science chapters of the book focus-with an eye to the development of the ideal SERM-on the complex mechanisms of estrogen action, including ligand-dependent conformational changes in alpha and beta, and the recruitment of co-activators and co-repressors which modulate the estrogen receptor transcriptional activity and contribute to its crosstalk with growth factor signaling. The clinical presentation reviews the data accumulated on currently available SERMs, primarily tamoxifen and raloxifene, in cancer treatment and prevention, as well as their effects on the reproductive, vascular, skeletal, and central nervous systems. A tentative approach to menopause-related health issues is also provided for women with and without a previous diagnosis of localized breast cancer.

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Selective Estrogen Receptor Modulators

Research and Clinical Applications

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Descriere completă

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