Carte Reverse Transcriptase Inhibitors in HIV/AIDS Therapy kowron

Reverse Transcriptase Inhibitors in HIV/AIDS Therapy

Autor: kowron
Limbă: engleză
Legare: Copertă tare
Disponibilitate: În depozitul extern în cantități mici
Expediem în 13-18 zile
1 150.92 lei
A magisterial survey of all aspects of the reverse transcriptase inhibitors (RTIs) used to treat HIV...

Informații despre carte

Autor
Limbă
engleză
Legare
Carte - Copertă tare
Publicat
2006
Pagini
528
EAN
9781588296498
ISBN
1588296490
Enbook ID
01430558
Greutate
967
Dimensiuni
155 x 235 x 34

Descriere completă

A magisterial survey of all aspects of the reverse transcriptase inhibitors (RTIs) used to treat HIV/AIDS, including drug discovery, pharmacology, development of drug resistance, toxicity, and prevention of mother-to-child transmission of HIV/AIDS. The authors synthesize our current understanding of the role of reverse transcriptase in the viral life cycle, describe the discovery and development of eight nucleoside and nucleotide analogs that represent milestones in treatment history, and thoroughly discuss the question of toxicity and resistance to this class of drugs. They also address three non-nucleoside RTIs and their pharmacokinetics and comparative clinical efficacy, new RTIs currently under development, and the impact of approved agents on treatment, in general, and on vertical transmission in the developing world.

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