Proteins

Name: Proteins
Brand: Springer-Verlag New York Inc.
SKU: 9781441963260
Price: 1222.93 RON
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Membrane Binding and Pore Formation

Autor: Gregor Anderluh, Jeremy Lakey

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Legare: Copertă tare

Editura: Springer-Verlag New York Inc.

Disponibilitate: În depozitul extern

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There are currently only two structures of pores available, of -toxin from Staphylococcus aureus and...

Informații despre carte

Autor

Gregor Anderluh, Jeremy Lakey

Limbă

engleză

Legare

Carte - Copertă tare

Publicat

2010

Pagini

172

EAN

9781441963260

ISBN

144196326X

Enbook ID

01423957

Editura

Springer-Verlag New York Inc.

Greutate

482

Dimensiuni

173 x 259 x 18

Descriere completă

There are currently only two structures of pores available, of -toxin from Staphylococcus aureus and hemolysin E from Escherichia coli. So what we know about these proteins was obtained over many years of intense experimentation. We have nevertheless, in the last couple of years, witnessed a significant rise in structural information on the soluble forms of pore-forming proteins. Surprisingly, many unexpected similarities with other proteins were noted, despite extremely low or insignificant sequence similarity. It appears that lipid membrane binding and formation of transmembrane channels is achieved in many cases by a limited repertoire of structures. This book describes how several of the important pore forming toxin families achieve membrane binding and which structural elements are used for formation of transmembrane pores. Our contributors have thus provided the means for a comparative analysis of several unrelated families.

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Proteins

Membrane Binding and Pore Formation

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