Protein Targeting Compounds

Name: Protein Targeting Compounds
Brand: Springer International Publishing AG
SKU: 9783319224725
Price: 804.22 RON
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Prediction, Selection and Activity of Specific Inhibitors

Autor: Thomas Böldicke

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Legare: Copertă tare

Editura: Springer International Publishing AG

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This book presents an overview of the most relevant protein knockdown techniques. Readers will find...

Informații despre carte

Autor

Thomas Böldicke

Limbă

engleză

Legare

Carte - Copertă tare

Publicat

2015

Pagini

288

EAN

9783319224725

ISBN

3319224727

Enbook ID

09389380

Editura

Springer International Publishing AG

Greutate

601

Dimensiuni

155 x 235 x 23

Descriere completă

This book presents an overview of the most relevant protein knockdown techniques. Readers will find a description of the generation and use of recombinant human antibodies, ER intrabodies and peptides as well as a description of the working mechanism and potential of the inhibitory action of each of these molecules. The book will also describe the selection and activity of a number of phosphatases, aptamers and allosteric modulators, focusing on A G protein coupled receptors. The book starts with a chapter on the in silico prediction of target-inhibitor interactions.§§Key aspects of this book are:§§- Selection strategies for monoclonal and recombinant human antibodies §§- Selection strategies for ER intrabodies, peptides and aptamers §§- Examples of the most efficient inhibitors and their applications in protein biochemistry and cell biology§§- Antibodies for cancer therapy and inhibitors of angiogenesis.§§The book will be of great interesting to scientists and students working in the life sciences on all areas related to protein biology. The variety of methods to modulate the activities of specific proteins which are introduced here will be of great benefit to the reader who is interested in general protein research or to readers who have very specific protein related questions.§

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Protein Targeting Compounds

Prediction, Selection and Activity of Specific Inhibitors

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