Protein Interaction Networks

Name: Protein Interaction Networks
Brand: Cambridge University Press
SKU: 9780521888950
Price: 524.69 RON
Availability: InStock

Computational Analysis

Autor: Aidong Zhang

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Legare: Copertă tare

Editura: Cambridge University Press

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524.69 lei

The analysis of protein-protein interactions is fundamental to the understanding of cellular organiz...

Informații despre carte

Autor

Aidong Zhang

Limbă

engleză

Legare

Carte - Copertă tare

Publicat

2009

Pagini

292

EAN

9780521888950

ISBN

0521888956

Enbook ID

02049261

Editura

Cambridge University Press

Greutate

Dimensiuni

180 x 260 x 21

Descriere completă

The analysis of protein-protein interactions is fundamental to the understanding of cellular organization, processes, and functions. Proteins seldom act as single isolated species; rather, proteins involved in the same cellular processes often interact with each other. Functions of uncharacterized proteins can be predicted through comparison with the interactions of similar known proteins. Recent large-scale investigations of protein-protein interactions using such techniques as two-hybrid systems, mass spectrometry, and protein microarrays have enriched the available protein interaction data and facilitated the construction of integrated protein-protein interaction networks. The resulting large volume of protein-protein interaction data has posed a challenge to experimental investigation. This book provides a comprehensive understanding of the computational methods available for the analysis of protein-protein interaction networks. It offers an in-depth survey of a range of approaches, including statistical, topological, data-mining, and ontology-based methods. The author discusses the fundamental principles underlying each of these approaches and their respective benefits and drawbacks, and she offers suggestions for future research.

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Protein Interaction Networks

Computational Analysis

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