Carte Probability Models for DNA Sequence Evolution Richard Durrett

Probability Models for DNA Sequence Evolution

Limbă: engleză
Legare: Copertă tare
Disponibilitate: În depozitul extern
Expediem în 10-18 zile
1 009.29 lei
As a starting point the authors address the fundamental question "What underlying forces are respons...

Informații despre carte

Limbă
engleză
Legare
Carte - Copertă tare
Publicat
2008
Pagini
431
EAN
9780387781686
ISBN
0387781684
Enbook ID
01247776
Greutate
614
Dimensiuni
164 x 244 x 30

Descriere completă

As a starting point the authors address the fundamental question "What underlying forces are responsible for the observed patterns of variability, given a collection of DNA sequences?" In approaching this question they introduce and analyze a number of probability models: the Wright-Fisher model, the coalescent, the infinite alleles model, and the infinite sites model. They then discuss the complications that come from nonconstant population size, recombination, population subdivision, and three forms of natural selection: directional selection, balancing selection, and background selection. These theoretical results set the stage for the investigation of various statistical tests to detect departures from "neutral evolution."

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