Post-Structural Genomics

Name: Post-Structural Genomics
Brand: VDM Verlag
SKU: 9783639113167
Price: 329.64 RON
Availability: InStock

Correlate Protein Sequence, Structure, and Function

Autor: Zhiyan Fu

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Legare: Carte broșată

Editura: VDM Verlag

Disponibilitate: În depozitul extern

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329.64 lei

One of the goals the post-genomic era is to use§protein sequence and structure data to learn about§t...

Informații despre carte

Autor

Zhiyan Fu

Limbă

engleză

Legare

Carte - Carte broșată

Publicat

2008

Pagini

132

EAN

9783639113167

ISBN

3639113160

Enbook ID

06820202

Editura

VDM Verlag

Greutate

194

Dimensiuni

155 x 227 x 9

Descriere completă

One of the goals the post-genomic era is to use§protein sequence and structure data to learn about§the function of these proteins in normal and disease§states. In the omics era, computational methods§constitute a valuable tool, because they can easily§process large amounts of data and provide useful and§instant information relevant in biomedical research.§This book described using computational approaches to§study the effects of genetic mutations in proteins,§with the general aim of correlating protein sequence,§structure, and function. Our works focus on§identifying whether genotype/phenotype relationship§can be learned from protein sequence and structuralinformation, whether protein structure prediction§methods are accurate enough to provide useful§information when the experimental structures are not§available, and finally to combine this information to§predict and understand the effect of mutations on§clinical phenotype and drug responses. The approaches§developed in this work enable a systematic,§comprehensive, and quantitative analysis of§disease-related mutations and establish a paradigm to§study genotype/phenotype correlations.

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Post-Structural Genomics

Correlate Protein Sequence, Structure, and Function

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