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Carte Poly(ADP-Ribose) Polymerase Alexei V. Tulin

Poly(ADP-Ribose) Polymerase

Methods and Protocols

Autor: Alexei V. Tulin
Limbă: engleză
Legare: Copertă tare
Editura: Springer, Berlin
Disponibilitate: În depozitul extern
Expediem în 10-13 zile
1 187.68 lei
This detailed volume explores poly(ADP-ribose) polymerases (PARPs) in the biology of eukaryotes and...

Informații despre carte

Autor
Alexei V. Tulin
Limbă
engleză
Legare
Carte - Copertă tare
Publicat
2022
Pagini
446
EAN
9781071628904
Enbook ID
41459525
Editura
Springer, Berlin
Greutate
1015
Dimensiuni
178 x 254 x 31

Descriere completă

This detailed volume explores poly(ADP-ribose) polymerases (PARPs) in the biology of eukaryotes and their relevance to human health. Beginning with a section on the detection and quantification of poly(ADP-ribose) polymer (pADPr), the book continues by delving into the identification of protein targets, functional analysis, the poly(ADP-ribosyl)ating pathway in chromatin and genes expression, as well as the use of animal models and PARP1 inhibitor design and testing, and more. Written for the highly successful Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step and readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and up-to-date, Poly(ADP-Ribose) Polymerase: Methods and Protocols, Third Edition presents essential new and classical methods for studying the pADPr-pathway.

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