Peste 4 milioane de titluri în engleză și alte limbi! Descoperă-ți noua poveste astăzi!

Pharmaceutical Process Chemistry for Synthesis - Rethinking the Routes to Scale-Up

Name: Pharmaceutical Process Chemistry for Synthesis - Rethinking the Routes to Scale-Up
Brand: John Wiley & Sons Inc
SKU: 9780470577554
Price: 871.36 RON
Availability: InStock

Autor: Peter J. Harrington

Limbă:

Legare: Copertă tare

Editura: John Wiley & Sons Inc

Disponibilitate: În depozitul extern

Expediem în 14-21 zile

871.36 lei

There is a need to inform the public that not all generic drugs are manufactured by the same process...

Informații despre carte

Autor

Peter J. Harrington

Limbă

engleză

Legare

Carte - Copertă tare

Publicat

2011

Pagini

376

EAN

9780470577554

ISBN

047057755X

Enbook ID

01388531

Editura

John Wiley & Sons Inc

Greutate

1158

Dimensiuni

221 x 281 x 25

Descriere completă

There is a need to inform the public that not all generic drugs are manufactured by the same process and that the different processes may have dramatically different environmental impacts. Two global forces are at odds today - the push for "greener" processes and the push for lower drug prices.§This book presents detailed discussions of the published process chemistry of the ten top-selling small molecule drugs in the US in 2007, information which is usually carefully protected by the current and future manufacturers. The author identifies methodology for manufacturing these blockbuster drugs most efficiently and to highlight methodology and strategies which might be used to expedite the manufacturing of the blockbusters of the future.§The content of each chapter reflects the range of tasks assigned to process chemists whose role on a process research and development team may be early route selection in one project or late troubleshooting of a difficult crystallization to produce a target which filters well and meets crystal size and purity specifications in another.Standardizes and expands upon information available in process patents for "blockbuster" drugs§There is a need to inform the public that generic versions of a drug may not be manufactured by the same process as brand-name drugs and that the different processes may have dramatically different environmental impacts. Two global forces are at odds today-the push for "greener" processes and the push for lower drug prices. This book brings this conflict into sharp focus by discussing in detail the published process chemistry for top-selling small molecule drugs.§Providing insights about process route selection, choice of reagents, and reaction conditions, Pharmaceutical Process Chemistry for Synthesis guides process chemists in identifying best processes for manufacturing these blockbuster drugs as they lose patent protection. Further, it highlights the strategies and methodology that might be useful for expediting the process research and development of the blockbusters of the future. Pharmaceutical Process Chemistry for Synthesis also:§Presents detailed discussions of the published process chemistry of Lipitor(r), Advair Diskus(r), Prevacid(r), Singulair(r), Seroquel(r), Effexor XR(r), Lexapro(r), and Actos(r)§Aids in the implementation of green chemistry in pharmaceutical manufacturing by comparing and contrasting known multiple processes to the same target§Summarizes the known process chemistry by discussing the advantages of one selected route for each drug§Reflects the range of tasks assigned to process chemists-i.e., manufacturing route selection, conversion of an intermediate to final target§A multi-level table of contents and comprehensive index of reagents for rapid access to specific information§Written from a refreshingly objective perspective, this book is essential for process chemists who need to devise practical syntheses for increasingly complex drugs in a constantly decreasing time frame.

Cele mai căutate

Categories

Authors

Publishers

Produse

Produse

Cele mai căutate

Categories

Authors

Publishers

Produse

Produse

Pharmaceutical Process Chemistry for Synthesis - Rethinking the Routes to Scale-Up

Informații despre carte

Descriere completă

S-ar putea să te intereseze

Jesse Ramsden (1735-1800)

Pharmaceutical Process Chemistry

Pharmaceutical Anti-Counterfeiting

Design of Heterogeneous Catalysts

Understanding General Chemistry

Inorganic Chemistry

My First Murder

Design & Realization of a Generator Test Bench Working with a Diesel & Biodiesel Blend

Family Violence Statistics Including Statistics on Strangers and Acquaintances

Big Trucks: A Touch-and-Feel Book

Chemistry

Sure Thing

The Joy of Watercolor

Nothing More - Guitar & Bass Tab Collection

Yakuza Tattoo

Diary of a Roblox Hacker - The Jd Trilogy: 3 Books in 1

Purple Heart Junction

Biological Mind

A Calling Out

The Little Sarasota Dining Book | 2016

Geschichte Und System Der Rechtsphilosophie in Grundzugen

Remote Laboratories

Thabo Mbeki's World: The Politics and Ideology of the South African President

The Biltmore Nursery: A Botanical Legacy