Peptide and Protein Interaction with Membrane Systems

Name: Peptide and Protein Interaction with Membrane Systems
Brand: Springer International Publishing AG
SKU: 9783319382739
Price: 551.7 RON
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Applications to Antimicrobial Therapy and Protein Drug Delivery

Autor: Sara Bobone

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Legare: Carte broșată

Editura: Springer International Publishing AG

Disponibilitate: În depozitul extern

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In her thesis, Sara Bobone outlines spectroscopic studies of antimicrobial peptides (AMPs) which are...

Informații despre carte

Autor

Sara Bobone

Limbă

engleză

Legare

Carte - Carte broșată

Publicat

2016

Pagini

140

EAN

9783319382739

ISBN

331938273X

Enbook ID

14277658

Editura

Springer International Publishing AG

Greutate

2467

Dimensiuni

155 x 8 x 9

Descriere completă

In her thesis, Sara Bobone outlines spectroscopic studies of antimicrobial peptides (AMPs) which are promising lead compounds for drugs used to fight multidrug resistant bacteria. Bobone shows that AMPs interact with liposomes and she clarifies the structure of pores formed by one of these molecules. These results help us to understand how AMPs are selective for bacterial membranes and how their activity can be finely tuned by modifying their sequence. Findings which solve several conundrums debated in the literature for years. In addition, Bobone uses liposomes as nanotemplates for the photopolymerization of hydrogels - exploiting the self- assembly properties of phospholipids. Bobone was able to trap an enzyme using nanometeric particles, while still allowing its activity by the diffusion of substrates and products through the network of the polymer. The innovative nano devices described in this thesis could solve many of the hurdles still hampering the therapeutic application of protein-based drugs.

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Peptide and Protein Interaction with Membrane Systems

Applications to Antimicrobial Therapy and Protein Drug Delivery

Informații despre carte

Descriere completă

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