Pathology of the Developing Mouse

Name: Pathology of the Developing Mouse
Brand: Taylor & Francis Inc
SKU: 9781420070088
Price: 1411.89 RON
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Autor: Brad Bolon

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Legare: Copertă tare

Editura: Taylor & Francis Inc

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Pathology of the Developing Mouse provides, in so far as feasible, one complete reference on the des...

Informații despre carte

Autor

Brad Bolon

Limbă

engleză

Legare

Carte - Copertă tare

Publicat

2015

Pagini

446

EAN

9781420070088

ISBN

9781420070088

Enbook ID

03164176

Editura

Taylor & Francis Inc

Greutate

1094

Dimensiuni

188 x 266 x 24

Descriere completă

Pathology of the Developing Mouse provides, in so far as feasible, one complete reference on the design, analysis, and interpretation of abnormal findings that may be detected in developing mice before and shortly after birth. In particular, this book is designed specifically to be not only a "how to do" manual for developmental pathology experimentation in mice but, more importantly, a "how to interpret" resource for pathologists and other biomedical scientists faced for the first or hundredth time with defining the significance of distorted features in some fantastic murine developmental monstrosity.

The topics covered in this volume include a full range of subjects encountered when building and wielding a developmental pathology tool kit:

baseline anatomic and physiologic traits of developing mice
principles of good experimental design and statistical analysis for mouse developmental pathology studies
procedures for anatomic pathology examinations, to evaluate structural changes at the macroscopic (gross), microscopic (cells and tissues), and ultrastructural (subcellular) levels, suing conventional autopsy-based or novel non-invasive imaging techniques;
methods for clinical pathology testing, to assess the biochemical and cellular composition of tissues and fluids;
options and protocols for in situ molecular pathology analysis, to undertake site-specific explorations of the various mechanisms responsible for producing adverse findings (i.e., "lesions") during development; and
well-referenced and illustrated guides to the interpretation of anatomic pathology and clinical pathology changes in the animal (embryos, fetuses, neonates, and juveniles) and its support system (placenta).

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