Patch-Clamp Methods and Protocols

Name: Patch-Clamp Methods and Protocols
Brand: Humana Press Inc.
SKU: 9781617377242
Price: 1307.15 RON
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Autor: Peter Molnar, James J. Hickman

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Editura: Humana Press Inc.

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Patch Clamp Methods and Protocols surveys the typical patch clamp applications and advises scientist...

Informații despre carte

Autor

Peter Molnar, James J. Hickman

Limbă

engleză

Legare

Carte - Carte broșată

Publicat

2010

Pagini

321

EAN

9781617377242

ISBN

1617377244

Enbook ID

01432302

Editura

Humana Press Inc.

Greutate

498

Dimensiuni

152 x 229 x 19

Descriere completă

Patch Clamp Methods and Protocols surveys the typical patch clamp applications and advises scientists on identifying problems and selecting the best technique in each instance. The experiments described aid the researcher in pursuing new areas of electrophysiology and using the patch clamp technique effectively. §The volume includes an extensive theoretical treatise concerning single channel kinetic analysis.Patch Clamp Methods and Protocols surveys the typical patch clamp applications and advises scientists on identifying problems and selecting the best technique in each instance. The experiments described require a basic level of electrophysiological training and aid the researcher in pursuing new areas of electrophysiology and using the patch clamp technique effectively. Patch Clamp Methods and Protocols is divided into three sections that cover the major areas of patch clamp application: Pharmacology, Physiology, and Biophysics. The first section provides examples and step by step instructions on how to use whole-cell and single-channel patch clamp methods for testing drugs in industrial settings. The second section provides a wide selection of patch clamp applications in physiological studies. The last part focuses on the biophysical applications of the patch clamp method using single channel recordings or statistical analysis of whole-cell currents in order to obtain parameters that describe ion channel properties or transmitter release. Individual techniques are explored within the area that they are applied most often. Researchers will find Patch Clamp Methods and Protocols to be an invaluable aid in the design and execution of a wide variety of patch clamp experiments, both on their own and in conjunction with other state-of-the-art methodologies.

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