Optimization in Drug Discovery

Name: Optimization in Drug Discovery
Brand: Humana Press Inc.
SKU: 9781627037419
Price: 1076.42 RON
Availability: InStock

In Vitro Methods

Autor: Gary W. Caldwell, Zhengyin Yan

Limbă:

Legare: Copertă tare

Editura: Humana Press Inc.

Disponibilitate: În depozitul extern

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Thoroughly revised and updated, Optimization in Drug Discovery: In Vitro Methods, Second Edition pre...

Informații despre carte

Autor

Gary W. Caldwell, Zhengyin Yan

Limbă

engleză

Legare

Carte - Copertă tare

Publicat

2013

Pagini

597

EAN

9781627037419

ISBN

1627037411

Enbook ID

02067260

Editura

Humana Press Inc.

Greutate

1339

Dimensiuni

178 x 254 x 38

Descriere completă

Thoroughly revised and updated, Optimization in Drug Discovery: In Vitro Methods, Second Edition presents a wide spectrum of in vitro assays including formulation, plasma binding, absorption and permeability, cytochrome P450 (CYP) and UDP-glucuronosyltransferases (UGT) metabolism, CYP inhibition and induction, drug transporters, drug-drug interactions via assessment of reactive metabolites, genotoxicity, and chemical and photo-mutagenicity assays. Written for the Methods in Pharmacology and Toxicology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible protocols, and tips on troubleshooting and avoiding known pitfalls. Expert authors have developed and utilized these in vitro assays to achieve drug-like characteristics in addition to efficacy properties and good safety profiles of drug candidates.§Comprehensive and up-to-date, Optimization in Drug Discovery: In Vitro Methods, Second Edition aims to guide researchers down the difficult path to successful drug discovery and development.§

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Optimization in Drug Discovery

In Vitro Methods

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