Carte Nuclear Factor  B R. Beyaert

Nuclear Factor B

Regulation and Role in Disease

Autor: R. Beyaert
Limbă: engleză
Legare: Carte broșată
Editura: Springer
Disponibilitate: În depozitul extern în cantități mici
Expediem în 13-18 zile
583.60 lei
The transcription factor NF-kappaB and the signaling pathways regulating its activity constitute a p...

Informații despre carte

Autor
Limbă
engleză
Legare
Carte - Carte broșată
Publicat
2012
Pagini
426
EAN
9789401039833
ISBN
9401039836
Enbook ID
02184486
Editura
Greutate
698
Dimensiuni
160 x 240 x 24

Descriere completă

The transcription factor NF-kappaB and the signaling pathways regulating its activity constitute a paradigm of membrane to nucleus communication. NF-kappaB is central to a number of cellular functions including cell proliferation, apoptosis, and cellular differentiation. This transcription factor also plays essential roles in innate and acquired immunity, and its deregulation leads to important human diseases such as inflammation and cancer. Therefore NF-kappaB, together with the signaling pathways leading to its activation, constitute an attractive therapeutic target. §This book is the first to review and synthesize our knowledge on this interesting transcription factor. It will be of great interest for those entering or already actively working in the NF-kappaB field, as well as a valuable reference for students, established researchers, or clinicians with wider interests in the fields of molecular cell biology and biomedicine.

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