This book presents a collection of research papers that aim to explore how managers, practitioners, and policymakers can address the challenges of DT with particular reference to the topics of organizational change, digital work, and individual behaviors. Each chapter offers insights into how to confront DT in order to support work within modern organizations and society. The plurality of views offered makes this book particularly relevant for scholars, companies, and public sector organizations. The content of the book is based on the revised versions of a selection of the best papers (original double-blind peer-reviewed contributions) presented at the annual conference of the Italian chapter of AIS which took place in Turin, Italy, in October 2023.