Multiparticulate System For Peptic Ulcer

Name: Multiparticulate System For Peptic Ulcer
Brand: LAP Lambert Academic Publishing
SKU: 9783845407241
Price: 304.21 RON
Availability: InStock

Novel Drug Delivery System For Helicobacter Pylori Induced Peptic Ulcer

Autor: Vinay Pandit, Sarasija Suresh

Limbă:

Legare: Carte broșată

Editura: LAP Lambert Academic Publishing

Disponibilitate: La editor doar la comandă

Expediem în 17-27 zile

304.21 lei

The discovery of Helicobacter pylori as the cause of peptic ulcer has revolutionized anti-ulcer trea...

Informații despre carte

Autor

Vinay Pandit, Sarasija Suresh

Limbă

engleză

Legare

Carte - Carte broșată

Publicat

2012

Pagini

132

EAN

9783845407241

Enbook ID

07044605

Editura

LAP Lambert Academic Publishing

Greutate

213

Dimensiuni

150 x 220 x 8

Descriere completă

The discovery of Helicobacter pylori as the cause of peptic ulcer has revolutionized anti-ulcer treatment. The current treatment includes a combination of antibiotics with proton pump inhibitors or H2 receptor antagonist1,2. Clarithromycin and omeprazole combination has become popular and best choice for treating peptic ulcer associated with H. pylori infection3. Gastro retentive dosage forms have the potential for increased residence in stomach along with site-specific drug delivery. Hydrodynamic drug delivery systems (HBS) are one such systems that has increased gastric residence providing an increased local action at the ulcer site4. Clarithromycin, effective in H.pylori infection treatment was chosen as model drug. Extended release and retention in upper gastro intestinal tract would be most advantageous, optimizing the combination therapy of peptic ulcer complicated with H.pylori. Omeprazole was formulated as fast dissolving enteric-coated pellets by using extrusion spheronisation technique. Enteric coating material used was Eudragit 30D-L-55.

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Multiparticulate System For Peptic Ulcer

Novel Drug Delivery System For Helicobacter Pylori Induced Peptic Ulcer

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Descriere completă

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