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Carte Molecular Recognition F S Dukhovich

Molecular Recognition

Pharmacological Aspects

Autor: F S Dukhovich
Limbă: engleză
Legare: Copertă tare
Editura: Nova Science Publishers Inc
Disponibilitate: șansă 50%
Şanse de a obține acest titlu
686.74 lei
In the monograph recognition of the receptors by drugs is described as a complex phenomenon that has...

Informații despre carte

Autor
F S Dukhovich
Limbă
engleză
Legare
Carte - Copertă tare
Publicat
2004
Pagini
214
EAN
9781590338872
ISBN
9781590338872
Enbook ID
06434750
Editura
Nova Science Publishers Inc
Greutate
616
Dimensiuni
183 x 262 x 18

Descriere completă

In the monograph recognition of the receptors by drugs is described as a complex phenomenon that has not been yet entirely understood. The description of molecular structure information necessary to achieve specific receptor without getting lost among huge amounts of non-specific acceptors is present. Various examples of receptor'' binding features for narcotic analgetics, neuroleptics, tranquilisators, ligands of acetylcholine receptors. The three stages of drug interaction with acceptors are considered, namely, distant stage, stage of orientation of the molecule on the acceptor, stage of molecule fixation. Kinetics and thermodynamics of these stages as well as factors preventing drug binding to non-specific acceptors are described. Some considerations concerning methods of changing activity and selectivity of drugs are given. Literature information needed for analysis of molecular mechanisms of interactions between drugs and receptors is present.

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