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Molecular Cytogenetics

Name: Molecular Cytogenetics
Brand: Humana Press Inc.
SKU: 9781588290069
Price: 825.19 RON
Availability: InStock

Protocols and Applications

Autor: Yao-Shan Fan

Limbă:

Legare: Copertă tare

Editura: Humana Press Inc.

Disponibilitate: În depozitul extern

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825.19 lei

The new techniques of molecular cytogenetics, mainly fluorescence in situ hybridization (FISH) of DN...

Informații despre carte

Autor

Yao-Shan Fan

Limbă

engleză

Legare

Carte - Copertă tare

Publicat

2002

Pagini

414

EAN

9781588290069

ISBN

1588290069

Enbook ID

02717169

Editura

Humana Press Inc.

Greutate

883

Dimensiuni

155 x 235 x 31

Descriere completă

The new techniques of molecular cytogenetics, mainly fluorescence in situ hybridization (FISH) of DNA probes to metaphase chromosomes or interphase nuclei, have been developed in the past two decades. Many FISH techniques have been implemented for diagnostic services, whereas some others are mainly used for investigational purposes. Several hundreds of FISH probes and hybridization kits are now commercially available, and the list is growing rapidly. FISH has been widely used as a powerful diagnostic tool in many areas of medicine including pediatrics, medical genetics, maternal fetal medicine, reproductive medicine, pathology, hematology, and oncology. Frequently, a physician may be puzzled by the variety of FISH techniques and wonder what test to order. It is not uncommon that a sample is referred to a laboratory for FISH without indicating a specific test. On the other hand, a cytogeneticist or a technologist in a laboratory needs, from case to case, to determine which procedure to perform and which probe to use for an informative result. To obtain the best results, one must use the right DNA probes and have reliable protocols and measures of quality assurance in place. Also, one must have sufficient knowledge in both traditional and molecular cytogenetics, as well as the particular areas of medicine for which the test is used in order to appropriately interpret the FISH results, and to correlate them with clinical diagnosis, treatment, and prognosis.

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Molecular Cytogenetics

Protocols and Applications

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