Molecular Allergy Diagnostics

Innovation for a Better Patient Management

Autor: Jörg Kleine-Tebbe, Thilo Jakob

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Legare: Carte broșată

Editura: Springer International Publishing AG

Disponibilitate: În depozitul extern

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702.77 lei

This book, based on a recent German publication, offers an overview of basic data and recent develop...

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Autor

Jörg Kleine-Tebbe, Thilo Jakob

Limbă

engleză

Legare

Carte - Carte broșată

Publicat

2018

Pagini

531

EAN

9783319825939

Enbook ID

20118812

Editura

Springer International Publishing AG

Greutate

1028

Dimensiuni

236 x 155 x 34

Descriere completă

This book, based on a recent German publication, offers an overview of basic data and recent developments in the groundbreaking field of molecular allergology. It comprehensively explores the origin and structure of single allergen molecules ("components") and their utility in improving the management of type I, IgE-mediated allergic reactions and disorders like allergic respiratory diseases, food allergies, and anaphylaxis. Highly specific testing, called component-resolved diagnostics, aims to identify and utilize single molecules. Over 200 single allergens from plant or animal sources have been applied to single or multiplex laboratory testing for the presence of allergen-specific IgE. This leap in assay sensitivity and specificity has led to three major advances in patient management: discrimination between primary allergic sensitization and complex cross-reactivity, recognition of IgE profiles for certain allergens and identification of patients most likely to benefit from allergen-specific immunotherapy. The book discusses in detail the benefits and limitations of this 21st century technology, and offers suggestions for the use of molecular allergology in routine clinical practice. It is a "must read" for physicians treating allergic patients as well as scientists interested in natural allergic molecules and their interactions with the human immune system.

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Molecular Allergy Diagnostics

Innovation for a Better Patient Management

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