Modeling Cellular Signaling Systems

Name: Modeling Cellular Signaling Systems
Brand: LAP Lambert Academic Publishing
SKU: 9783846537565
Price: 283.22 RON
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An Abstraction-Refinement Approach

Autor: Diana Hermith

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Editura: LAP Lambert Academic Publishing

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At the cellular level, theorize about the molecular mechanisms of cells to communicate with the envi...

Informații despre carte

Autor

Diana Hermith

Limbă

engleză

Legare

Carte - Carte broșată

Publicat

2011

Pagini

128

EAN

9783846537565

ISBN

384653756X

Enbook ID

06960014

Editura

LAP Lambert Academic Publishing

Greutate

209

Dimensiuni

150 x 220 x 8

Descriere completă

At the cellular level, theorize about the molecular mechanisms of cells to communicate with the environment implies to take into consideration concurrent processes, elements, and relationships that define the functionality of cells over time. The cell-membrane, the surface that acts as a boundary contains many receptors which are responsible for interacting with diverse signaling molecules and recognize external information that affects the behavior in a cell. Each receptor detects specific molecules that may bind to it, which activates signaling pathways that regulate molecular mechanisms, the flow and the processing of biochemical information. There is a special class of receptors that constitutes a common target of pharmaceutical drugs, the G protein-coupled receptors (GPCRs). These receptors interact with their respective Guanine nucleotide-binding proteins (G Proteins) to induce an intracellular signaling. In this thesis we study, in a compositional way, interesting biological scenarios in the context of signaling biochemical networks by using the nTCC calculus, a non-deterministic temporal extension of Concurrent Constraint Programming (CCP).

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Modeling Cellular Signaling Systems

An Abstraction-Refinement Approach

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Descriere completă

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