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Carte Metallopharmaceuticals I Michael J. Clarke

Metallopharmaceuticals I

DNA Interactions

Autor: Michael J. Clarke, Peter J. Sadler
Limbă: engleză
Legare: Carte broșată
Editura: Springer-Verlag Berlin and Heidelberg GmbH & Co. KG
Disponibilitate: În depozitul extern
Expediem în 5-8 zile
1 098.37 lei
Each volume provides the reader, whether engaged in chemistry, biochemistry, biology or molecular me...

Informații despre carte

Autor
Michael J. Clarke, Peter J. Sadler
Limbă
engleză
Legare
Carte - Carte broșată
Publicat
2010
Pagini
200
EAN
9783642084409
ISBN
3642084400
Enbook ID
01653448
Editura
Springer-Verlag Berlin and Heidelberg GmbH & Co. KG
Greutate
338
Dimensiuni
155 x 235 x 12

Descriere completă

Each volume provides the reader, whether engaged in chemistry, biochemistry, biology or molecular medicine, with a comprehensive summary and critical overview of a topic of great current interest written by leading international experts.Inorganic compounds offer much scope for the design of novel and therapeutic agents. The widespread use of paramagnetic metal complexes as effective contrast agents for magnetic resonsance imaging (e.g. Gd) demonstrates that the toxicity of metals can be finely controlled via the approriate choice of ligands. The successful targeting of radioisotopes again depends on ligand design and metal oxidation state. Bismuth and gold complexes have long been used in medicine but only recently have advances been made in understanding the molecular basis of their mechanism of action. New areas with clinical potential include the use of polyoxometallates and fullerenes as antiviral agents and vanadium complexes as insulin mimetics.

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