Malaria

Name: Malaria
Brand: Springer-Verlag New York Inc.
SKU: 9781441921024
Price: 553.38 RON
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Genetic and Evolutionary Aspects

Autor: Krishna R. Dronamraju, Paolo Arese

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Editura: Springer-Verlag New York Inc.

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This book was originally conceived at a conference at the University of Turin in Italy. The conferen...

Informații despre carte

Autor

Krishna R. Dronamraju, Paolo Arese

Limbă

engleză

Legare

Carte - Carte broșată

Publicat

2010

Pagini

190

EAN

9781441921024

ISBN

1441921028

Enbook ID

02716941

Editura

Springer-Verlag New York Inc.

Greutate

320

Dimensiuni

155 x 235 x 10

Descriere completă

This book was originally conceived at a conference at the University of Turin in Italy. The conference was organized to examine the so-called Malaria Hypothesis , that is to say, the higher fitness of t- lassemia heterozygotes in a malarial environment, and to pay tribute to the proponent of that hypothesis, J.B.S. Haldane. Contributors to this book examine certain genetic and evolutionary aspects of malaria which is a major killer of human populations, especially in Africa and Asia. There were attempts to discredit Haldane s contribution from two directions: (a) it has been suggested that the Malaria Hypothesis was known long before Haldane and that there was nothing original about his idea (Lederberg 1999), and that (b) the hypothesis of heterozygote su- riority was first suggested by the Italian biologist Giuseppe Montalenti who communicated his idea to Haldane (Allison 2004). Surely, both c- not be right. In fact, the evidence presented in this book clearly indicates that both are wrong. Haldane s malaria hypothesis has stimulated a great deal of research on the genetic, evolutionary and epidemiological aspects of malaria d- ing the last 50 years. It has opened up a whole new chapter in the study of infectious diseases. It deserves serious consideration. For helpful discussions we thank Lucio Luzzatto, Alberto Piazza, Guido Modiano and David Roberts.

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Malaria

Genetic and Evolutionary Aspects

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