Lipid Uptake in Living Cells Visualized by Single Molecule Microscopy

Name: Lipid Uptake in Living Cells Visualized by Single Molecule Microscopy
Brand: VDM Verlag Dr. Mueller E.K.
SKU: 9783836482479
Price: 254.04 RON
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Single Molecule Microscopy as a Research Tool for Molecular Cellbiology

Autor: Sebastian Rhode

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Editura: VDM Verlag Dr. Mueller E.K.

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254.04 lei

In recent years single molecule microscopy (SMM) became a very important tool in cell biology. Compa...

Informații despre carte

Autor

Sebastian Rhode

Limbă

engleză

Legare

Carte - Carte broșată

Publicat

2008

Pagini

116

EAN

9783836482479

ISBN

3836482479

Enbook ID

07064804

Editura

VDM Verlag Dr. Mueller E.K.

Greutate

163

Dimensiuni

152 x 229 x 6

Descriere completă

In recent years single molecule microscopy (SMM) became a very important tool in cell biology. Compared to other microscopic methods this technique offers the possibility to probe molecules in living cells with high temporal and lateral resolution. These advantages allow measuring the entire statistical distribution of a parameter. Therefore this method can be used to analyze heterogeneous probes, because it avoids the problems of averaging typically limiting investigations of ensembles. Another major advantage of this method, which is especially relevant for this work, is the possibility to determine the position of a labeled particle or molecule with accuracy which is about one order of magnitude below the diffraction limit of conventional optical microscopy. In the presented work all these benefits are utilized to answer questions concerning lipoprotein related lipid uptake and the behavior of lipids within the plasma membrane. Part of this work deals with the combination of atomic force microscopy (AFM) and fluorescence microscopy. The advantages of both methods are combined in one setup.

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Lipid Uptake in Living Cells Visualized by Single Molecule Microscopy

Single Molecule Microscopy as a Research Tool for Molecular Cellbiology

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