Leucocyte Trafficking

Name: Leucocyte Trafficking
Brand: Springer-Verlag Berlin and Heidelberg GmbH & Co. KG
SKU: 9783662053997
Price: 893.42 RON
Availability: InStock

The Role of Fucosyltransferases and Selectins

Autor: A. Hamann, Khusru Asadullah, A. Schottelius

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Editura: Springer-Verlag Berlin and Heidelberg GmbH & Co. KG

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An essential component of inflammation is the migration of circulating leukocytes from blood into ti...

Informații despre carte

Autor

A. Hamann, Khusru Asadullah, A. Schottelius

Limbă

engleză

Legare

Carte - Carte broșată

Publicat

2013

Pagini

242

EAN

9783662053997

ISBN

3662053993

Enbook ID

02176289

Editura

Springer-Verlag Berlin and Heidelberg GmbH & Co. KG

Greutate

339

Dimensiuni

148 x 14 x 15

Descriere completă

An essential component of inflammation is the migration of circulating leukocytes from blood into tissues. This process is characterized by a multistep paradigm of sequential cell adhesion and activation events that lead to the extravasation of specific leukocyte subsets to different tissues in health and disease. The first step of leukocyte extravasation, the rolling of leukocytes, is primarily mediated by the interactions of selectins and their ligands. It has recently become evident that fucosyltransferases are crucial for selectin ligand synthesis, inflammation, and skin homing. This book provides an in-depth overview of the mechanisms of leukocyte trafficking and of the molecular mechanisms of selectin/selectin ligand interactions and discusses options for pharmacological intervention to treat inflammatory diseases.§

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Leucocyte Trafficking

The Role of Fucosyltransferases and Selectins

Informații despre carte

Descriere completă

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