Kinase Screening and Profiling

Methods and Protocols

Autor: Said A. Goueli, Hicham Zegzouti

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Legare: Carte broșată

Editura: Humana Press Inc.

Disponibilitate: În depozitul extern

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This volume focuses on screening and profiling kinase inhibitors or activators. Chapters in this boo...

Informații despre carte

Autor

Said A. Goueli, Hicham Zegzouti

Limbă

engleză

Legare

Carte - Carte broșată

Publicat

2016

Pagini

223

EAN

9781493949236

ISBN

1493949233

Enbook ID

18049989

Editura

Humana Press Inc.

Greutate

4511

Dimensiuni

178 x 254 x 13

Descriere completă

This volume focuses on screening and profiling kinase inhibitors or activators. Chapters in this book cover several facets of the drug discovery processes starting with target identification, and assay development and screening chemical libraries for hit identification and lead optimization. The profiling portion of Kinase Screening and Profiling: Methods and Protocols discusses several strategies and techniques that are required to minimize off target hits and reduce cellular toxicities that are caused by liability kinases. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Timely and authoritative, Kinase Screening and Profiling: Methods and Protocols, will benefit scientists and researchers who are interested in exploring the role of kinases in academic, as well as pharmaceutical research.

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Kinase Screening and Profiling

Methods and Protocols

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