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Carte Killer Lymphocytes Gideon Berke

Killer Lymphocytes

Autor: Gideon Berke, William R. Clark
Limbă: engleză
Legare: Carte broșată
Editura: Springer Netherlands
Disponibilitate: În depozitul extern
Expediem în 5-8 zile
826.09 lei
We have known about the existence of killer lymphocytes since 1960, when they were discovered in con...

Informații despre carte

Autor
Gideon Berke, William R. Clark
Limbă
engleză
Legare
Carte - Carte broșată
Publicat
2007
Pagini
361
EAN
9781402065637
ISBN
1402065639
Enbook ID
01417493
Editura
Springer Netherlands
Greutate
536
Dimensiuni
155 x 235 x 21

Descriere completă

We have known about the existence of killer lymphocytes since 1960, when they were discovered in connection with transplant rejection in vivo. Since then we have uncovered at least five subsets of lymphocytes that can kill other cells in vitro, establishing the study of cell-mediated cytotoxicity (CMC) as a major field of immunological inquiry. Berke and Clark summarize the extensive literature based on the study of CMC in vitro. Several important questions about killer cells have now been answered, for example, how they go about destroying other cells. Research ultimately revealed at least three lytic mechanisms available to killer lymphocytes. But do killer cells actually use these mechanisms in vivo? The possible involvement of CMC in transplant rejection, control of intracellular parasites, cancer, autoimmunity, and immune homeostatic regulation is analyzed in detail, yielding some surprising findings, and outlining important questions that remain unanswered. §This extensively documented, comprehensive survey of cell-mediated cytotoxicity traces the history of killer lymphocytes from 1960 to the present, providing a definitive resource for specialists and non-specialists alike.

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