Integrin-mediated Interactions between Cells and Biomimetic Materials

Name: Integrin-mediated Interactions between Cells and Biomimetic Materials
Brand: VDM Verlag Dr. Mueller E.K.
SKU: 9783639042009
Price: 436.13 RON
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Autor: Robert Knerr

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Editura: VDM Verlag Dr. Mueller E.K.

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436.13 lei

Based on the idea of self-assembled monolayers of alkanethiols on gold, it was the goal of this thes...

Informații despre carte

Autor

Robert Knerr

Limbă

engleză

Legare

Carte - Carte broșată

Publicat

2008

Pagini

232

EAN

9783639042009

ISBN

363904200X

Enbook ID

06813792

Editura

VDM Verlag Dr. Mueller E.K.

Greutate

345

Dimensiuni

152 x 229 x 12

Descriere completă

Based on the idea of self-assembled monolayers of alkanethiols on gold, it was the goal of this thesis to develop a versatile model system for an efficient and straightforward characterization of cell - biomaterial interactions on PEG-rich surfaces. The necessary compounds for this model system should allow for mimicking the surface of polymeric poly(ethyleneglycol)-rich biomaterials used for the design of cell carriers. By evaluating the adsorption of proteins and the adhesion characteristics of mammalian cells on these artificial surfaces, conclusions can be drawn, on how polymers should be engineered to achieve an optimal adhesion, growth or proliferation of cells. In particular, the consequences of an attachment of peptidic cell adhesion peptides and growth factors had to be elucidated.

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Integrin-mediated Interactions between Cells and Biomimetic Materials

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