Immunological Synapse

Name: Immunological Synapse
Brand: Springer-Verlag Berlin and Heidelberg GmbH & Co. KG
SKU: 9783642038570
Price: 830.22 RON
Availability: InStock

Autor: Takashi Saito, Facundo D. Batista

Limbă:

Legare: Copertă tare

Editura: Springer-Verlag Berlin and Heidelberg GmbH & Co. KG

Disponibilitate: În depozitul extern

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830.22 lei

While the importance of the immune synapse as a dynamic cell junction that regulates intercellular c...

Informații despre carte

Autor

Takashi Saito, Facundo D. Batista

Limbă

engleză

Legare

Carte - Copertă tare

Publicat

2009

Pagini

255

EAN

9783642038570

ISBN

3642038573

Enbook ID

01650366

Editura

Springer-Verlag Berlin and Heidelberg GmbH & Co. KG

Greutate

626

Dimensiuni

155 x 235 x 21

Descriere completă

While the importance of the immune synapse as a dynamic cell junction that regulates intercellular communication and viral transmission is universally recognized, many of quantitative and qualitative details remain unsettled. The plasticity of this cell junction has to accommodate many very different binding partners and control the fate of interacting cells. It is likely that developmental changes in the state of the T cells or the APCs can impact the structure of the synapse. It is hoped that uncovering the ordered molecular rearrangement at the membrane will provide the long sought after clues for the remarkable functional sensitivity of T lymphocytes. These dynamic molecular interactions may eventually explain how engagement of the same TCR can generate different outcomes that resolve the immune challenges. The reviews in this issue present a broad slice of the many diverse topics that are currently intensely debated.

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