Histone Variants

Methods and Protocols

Autor: Guillermo A. Orsi, Genevi?ve Almouzni

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Editura: Humana Press Inc.

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This volume compiles methodologies used for detailed studies of histone variants, from their basic p...

Informații despre carte

Autor

Guillermo A. Orsi, Genevi?ve Almouzni

Limbă

engleză

Legare

Carte - Copertă tare

Publicat

2018

Pagini

359

EAN

9781493986620

ISBN

1493986627

Enbook ID

19354899

Editura

Humana Press Inc.

Greutate

921

Dimensiuni

178 x 254 x 26

Descriere completă

This volume compiles methodologies used for detailed studies of histone variants, from their basic properties to their functional roles in chromatin and as vectors of epigenetic information. Its four sections cover experimental approaches to probe the biochemistry of histone variants and variant nucleosomes; their dynamics throughout the cell cycle and at specific genomic locations; their functional impact on chromosome organization and genome stability; and their importance in development, disease and evolution. Written in the highly successful Methods in Molecular Biology series format, chapters include lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, illustrations on the expected results, and tips on troubleshooting and avoiding known pitfalls. This anthology brings together contributions from many of the most highly recognized investigators in this community. Cutting-edge and thorough, Histone Variants: Methods and Protocols is a valuable resource for anyone interested in exploring the experimental and collaborative possibilities in this evolving field.

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Histone Variants

Methods and Protocols

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