Histone Recognition

Name: Histone Recognition
Brand: Springer International Publishing AG
SKU: 9783319376660
Price: 553.26 RON
Availability: InStock

Autor: Ming-Ming Zhou

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Legare: Carte broșată

Editura: Springer International Publishing AG

Disponibilitate: În depozitul extern

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553.26 lei

This book provides a timely review of the role of histone modifications in epigenetic control of gen...

Informații despre carte

Autor

Ming-Ming Zhou

Limbă

engleză

Legare

Carte - Carte broșată

Publicat

2016

Pagini

282

EAN

9783319376660

ISBN

3319376667

Enbook ID

15194239

Editura

Springer International Publishing AG

Greutate

4453

Dimensiuni

155 x 235 x 16

Descriere completă

This book provides a timely review of the role of histone modifications in epigenetic control of gene expression. Topics covered include: basic mechanisms of molecular recognition of histone post-translational modification (PTMs); combinatorial readout of histone PTMs by tandem epigenome reader domains; genome-wide profiling of histone PTM interactions; small molecule modulation of histone PTM interactions and their potential as a new approach to therapeutic intervention in human diseases. All chapters were written by leading scientists who made the original key discoveries of the structure and mechanism of evolutionarily conserved reader domains, which serve to direct gene transcription in chromatin through interactions with DNA-packing histones in a PTM-sensitive manner.

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