Carte Histone Recognition Ming-Ming Zhou

Histone Recognition

Limbă: engleză
Legare: Copertă tare
Disponibilitate: În depozitul extern
Expediem în 10-13 zile
551.58 lei
This book provides a timely review of the role of histone modifications in epigenetic control of gen...

Informații despre carte

Limbă
engleză
Legare
Carte - Copertă tare
Publicat
2015
Pagini
282
EAN
9783319181011
ISBN
3319181017
Enbook ID
09255758
Greutate
720
Dimensiuni
155 x 235 x 243

Descriere completă

This book provides a timely review of the role of histone modifications in epigenetic control of gene expression. Topics covered include: basic mechanisms of molecular recognition of histone post-translational modification (PTMs); combinatorial readout of histone PTMs by tandem epigenome reader domains; genome-wide profiling of histone PTM interactions; small molecule modulation of histone PTM interactions and their potential as a new approach to therapeutic intervention in human diseases. All chapters were written by leading scientists who made the original key discoveries of the structure and mechanism of evolutionarily conserved reader domains, which serve to direct gene transcription in chromatin through interactions with DNA-packing histones in a PTM-sensitive manner.§

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