Gigaseal Formation in Patch Clamping

Name: Gigaseal Formation in Patch Clamping
Brand: Springer-Verlag Berlin and Heidelberg GmbH & Co. KG
SKU: 9783642391279
Price: 275.77 RON
Availability: InStock

With Applications of Nanotechnology

Autor: Majid Malboubi, Kyle Jiang

Limbă:

Legare: Carte broșată

Editura: Springer-Verlag Berlin and Heidelberg GmbH & Co. KG

Disponibilitate: În depozitul extern

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275.77 lei

This book presents an investigation of gigaseal formation using micro/nanotechnology. The aims of th...

Informații despre carte

Autor

Majid Malboubi, Kyle Jiang

Limbă

engleză

Legare

Carte - Carte broșată

Publicat

2013

Pagini

EAN

9783642391279

ISBN

3642391273

Enbook ID

01663928

Editura

Springer-Verlag Berlin and Heidelberg GmbH & Co. KG

Greutate

1766

Dimensiuni

155 x 235 x 7

Descriere completă

This book presents an investigation of gigaseal formation using micro/nanotechnology. The aims of the book are twofold. First, it explains the mechanisms of gigaseal formation using the latest discoveries. Second, it provides practical techniques for frequent formation of high resistance seals. The formation of a high-resistance electrical seal, also known as a gigaseal, between a cell membrane and a glass micropipette tip is essential in patch-clamp experiments. Even though four decades have passed since the introduction of the patch-clamping technique by Neher and Sakmann, gigaseal formation remains an obstacle in developing the high-throughput ion channel screening systems required by the pharmaceutical industry. Here the authors share their latest methods for achieving gigaseal formation and describe techniques that are highly desirable at both research and industrial levels. Nanotechnology has been found to be a powerful tool for studying and modifying glass micropipettes and in tackling the problem of gigaseal formation.

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Gigaseal Formation in Patch Clamping

With Applications of Nanotechnology

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Descriere completă

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