Genome Integrity

Name: Genome Integrity
Brand: Springer-Verlag Berlin and Heidelberg GmbH & Co. KG
SKU: 9783642072260
Price: 1656.56 RON
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Facets and Perspectives

Autor: Dirk-Henner Lankenau

Limbă:

Legare: Carte broșată

Editura: Springer-Verlag Berlin and Heidelberg GmbH & Co. KG

Disponibilitate: În depozitul extern

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This is the first book to give a full overview on genome integrity in different species. From microo...

Informații despre carte

Autor

Dirk-Henner Lankenau

Limbă

engleză

Legare

Carte - Carte broșată

Publicat

2010

Pagini

496

EAN

9783642072260

ISBN

3642072267

Enbook ID

01652390

Editura

Springer-Verlag Berlin and Heidelberg GmbH & Co. KG

Greutate

752

Dimensiuni

233 x 159 x 30

Descriere completă

This is the first book to give a full overview on genome integrity in different species. From microorganisms to humans, this volume provides an interdisciplinary overview of how genome integrity is maintained. Written by an international panel of experts, the book addresses the connection between genome integrity and human disease.Cells and viruses maintain a genome capable of multiplication, variation and heredity. A genome consists of chromosomes, each being built up of two complementary strands of nucleic acid known as DNA. Its chemical integrity, however, is under constant assault from metabolic mutagens, such as hydroxy-radicals, endonucleases, radiation, replication errors, and environmental mutagens. From microorganisms to humans, this volume provides an interdisciplinary overview of how genome integrity is maintained. The volume begins with DNA replication and continues with replicative DNA repair and pleiotropic protein interactions. Examples of human diseases are included and the cellular responses to radiation and genotoxic stress affecting whole genomes are reviewed.

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Genome Integrity

Facets and Perspectives

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