Carte Gastropodan hemocyanin Nurul Siddiqui

Gastropodan hemocyanin

Phenoloxidase activity, antigenicity and immunological relationship with alpha-macroglobulin

Limbă: engleză
Legare: Carte broșată
Disponibilitate: La editor doar la comandă
Expediem în 17-27 zile
304.61 lei
The copper containing oxygen transport protein hemocyanin (Hc) is vital for the survival of many ani...

Informații despre carte

Limbă
engleză
Legare
Carte - Carte broșată
Publicat
2012
Pagini
156
EAN
9783846589113
Enbook ID
07090688
Greutate
224
Dimensiuni
150 x 220 x 8

Descriere completă

The copper containing oxygen transport protein hemocyanin (Hc) is vital for the survival of many animals belonging to arthropodan and molluscan phyla. The functional units (FUs), which constitute a Hc molecule, each contain an active site with a pair of Cu atoms able to reversibly bind molecular oxygen. Phenoloxidases (POs), from which Hcs probably evolved, possess a similar active site with paired Cu atoms but, in contrast to Hcs, they oxidize phenolic substrates. Reports indicate that due to the active site similarity Hcs can be induced to carry out PO activity. That s why Hc became an interesting subject to explore its latent PO activity. Another important property of Hc is the immunogenic potency, which has led to therapeutic applications. This incited us to further study the antigenicity of Hc and the origin of this property. This research work exploited several analytical and separation techniques concerning protein purification-characterisation, measurement of the PO activity, analyses of the glycopeptides and detection of immunogenicity (ELISA).

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