Formulation & Evaluation of Dexamethasone Matrix

Name: Formulation & Evaluation of Dexamethasone Matrix
Brand: LAP LAMBERT Academic Publishing
SKU: 9786204983424
Price: 291.25 RON
Availability: InStock

Autor: Ravikant Gupta

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Editura: LAP LAMBERT Academic Publishing

Disponibilitate: În depozitul extern

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291.25 lei

The aim of this study is to prepare matrix tablets of dexamethasone, that can manage the various fac...

Informații despre carte

Autor

Ravikant Gupta

Limbă

engleză

Legare

Carte - Carte broșată

Publicat

2022

Pagini

EAN

9786204983424

ISBN

6204983423

Enbook ID

41375192

Editura

LAP LAMBERT Academic Publishing

Greutate

155

Dimensiuni

150 x 220 x 6

Descriere completă

The aim of this study is to prepare matrix tablets of dexamethasone, that can manage the various factors-Patient compliances and conveniences, Manage time for administrating the drug, Reduce multiple doses ofdexamethasone, Desired therapeutic effect.The basic approach in development of matrix tablets is the use of co-processed diluents like micro crystalline cellulose (MCC), magnesium stearate, lactose etc and natural polymer like traganth gum provide slow disintegration of tablets after putting in oral cavity, thereby release the drug in stomach. The bioavailability of some drugs may be decreased due to absorption of drugs in saliva and also due to pregastric absorption of saliva containing dispersed drugs that pass down into the stomach.In this study I have chosen dexamethasone drug because it having half life of 4-6 hours and can be formulated as sustain type drug.Tablet formulation on the basis of optimized batch had 1.6% of dexamethasone with 98.4% excipients. In conclusion, it can be said that the studies were helpful in evolving sustain release or matrix tablets of dexamethasone.

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