Carte Evolutionary Computational Biology -Autoimmune Disorders Biplab Bhattacharjee

Evolutionary Computational Biology -Autoimmune Disorders

Comparison of Biochemical Pathways of Autoimmune disease in Human orthologs

Limbă: engleză
Legare: Carte broșată
Disponibilitate: În depozitul extern
Expediem în 8-11 zile
281.94 lei
Evolutionary conservation of protein interaction properties has been shown to be a valuable indicati...

Informații despre carte

Limbă
engleză
Legare
Carte - Carte broșată
Publicat
2011
Pagini
160
EAN
9783846535073
Enbook ID
06887764
Greutate
256
Dimensiuni
150 x 220 x 10

Descriere completă

Evolutionary conservation of protein interaction properties has been shown to be a valuable indication for functional importance.Rodent orthologs are more conserved in human and the human disease genes are functional in rat genome. Some are inherited disease gene are highly conserved in rat. The investigation of evolutionary rates among large sets of genes has become feasible with the availability of the genome sequences of human, rat & mouse. Evolutionary conservation of protein composition and biochemical properties is usually a valuable indication for the cellular importance of a specific protein complex. In this study we analyzed whether association rates of protein in 5 major biochemical pathways of autoimmune disorders are conserved during evolution, because evolutionary conservation of protein biochemical properties is usually a valuable indication of its importance.

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