Enzyme technology using Bacterial lipid modification enzyme LGT

Name: Enzyme technology using Bacterial lipid modification enzyme LGT
Brand: LAP Lambert Academic Publishing
SKU: 9783838323541
Price: 378.45 RON
Availability: InStock

Characterization of LGT with a new generic peptide assay and LGT-bioreactor prototype for lipopeptide synthesis

Autor: Krishnan Sankaran

Limbă:

Legare: Carte broșată

Editura: LAP Lambert Academic Publishing

Disponibilitate: În depozitul extern

Expediem în 5-8 zile

378.45 lei

Covalent lipid modification of proteins anchors hydrophilic proteins/peptides to hydrophobic surface...

Informații despre carte

Autor

Krishnan Sankaran

Limbă

engleză

Legare

Carte - Carte broșată

Publicat

2009

Pagini

208

EAN

9783838323541

Enbook ID

07084775

Editura

LAP Lambert Academic Publishing

Greutate

326

Dimensiuni

150 x 220 x 12

Descriere completă

Covalent lipid modification of proteins anchors hydrophilic proteins/peptides to hydrophobic surfaces and aid efficient performance in aqueous conditions as required in many biotechnological applications like ELISA, biosensors, targeted-drug delivery and liposomal integration. Lipid modification studied by him in bacteria extended the possibility of in vitro lipid modification, particularly for peptides. In this thesis the first enzyme of the pathway, phosphatidylglycerol:prolipoprotein diacylglyceryl transferase (Lgt), which catalyzes the bulk of the lipidation has been utilized in devising a small bioreactor prototype for in vitro peptide modification. To achieve this, a new generic synthetic peptide assay was designed and used for its kinetic characterization and enrichment. The packed bed reactor with continuous and total feed-back operation in batch mode converted 65% of the model hydrophilic peptide substrate to lipopeptide. The higher conversion rate achieved in this study demonstrated the feasibility of such a bioreactor for lipid modification of a variety of peptides for potential biotech applications.

S-ar putea să te intereseze

Clienții care au cumpărat această carte au mai cumpărat și

Cele mai căutate

Categories

Authors

Publishers

Produse

Produse

Cele mai căutate

Categories

Authors

Publishers

Produse

Produse

Enzyme technology using Bacterial lipid modification enzyme LGT

Characterization of LGT with a new generic peptide assay and LGT-bioreactor prototype for lipopeptide synthesis

Informații despre carte

Descriere completă

S-ar putea să te intereseze

Clienții care au cumpărat această carte au mai cumpărat și