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This detailed volume highlights the heterogeneity and plasticity of enteric glial cells and explores their contributions to both GI homeostasis and disease pathophysiology. Through an interdisciplinary approach, the book brings together expertise from neurobiology, immunology, physiology, pharmacology, and pathology to provide a comprehensive perspective on the enteric nervous system and its glial components. It explores electrophysiological techniques, the relationship between enteric glia and the gut microbiota, advances in immunohistochemistry, the influence of the gut-brain axis on neurodegenerative diseases and mood disorders, and more. Written for the highly successful Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step and readily reproducible laboratory protocols, and tips for troubleshooting and avoiding known pitfalls.
Authoritative and practical, Enteric Glial Cells: Methods and Protocols serves as an ideal guide for understanding enteric glia but also for stimulating new research avenues that could lead to breakthroughs in treating a range of gastrointestinal and neurological disorders.
