Endotoxins: Structure, Function and Recognition

Name: Endotoxins: Structure, Function and Recognition
Brand: Springer
SKU: 9789048190775
Price: 1100.75 RON
Availability: InStock

Autor: Xiaoyuan Wang, Peter J. Quinn

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Legare: Copertă tare

Editura: Springer

Disponibilitate: În depozitul extern

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Endotoxins are potentially toxic compounds produced by Gram-negative bacteria including some pathoge...

Informații despre carte

Autor

Xiaoyuan Wang, Peter J. Quinn

Limbă

engleză

Legare

Carte - Copertă tare

Publicat

2010

Pagini

415

EAN

9789048190775

ISBN

9048190770

Enbook ID

01976746

Editura

Springer

Greutate

896

Dimensiuni

155 x 235 x 31

Descriere completă

Endotoxins are potentially toxic compounds produced by Gram-negative bacteria including some pathogens. Unlike exotoxins, which are secreted in soluble form by live bacteria, endotoxins are comprised of structural components of bacteria. §Endotoxins can cause a whole-body inflammatory state, sepsis, leading to low blood pressure, multiple organ dysfunction syndrome and death.§This book brings together contributions from researchers in the forefront of these subjects. It is divided into two sections: the first dealing with how endotoxins are synthesized and end up on the bacterial surface. The second discussed how endotoxins activate the Toll-like receptor TLR4 and, in turn, how TLR4 generates the molecular signals leading to infectious and inflammatory diseases.§The way endotoxins interact with the host cells is fundamental to understanding the mechanism of sepsis, and recent research on these aspects of endotoxins has served to illuminate previously undescribed functions of the innate immune system. This volume presents a description of endotoxins according to their genetic constitution, structure, function and mode of interaction with host cells.

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Endotoxins: Structure, Function and Recognition

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