Ectopeptidases

Name: Ectopeptidases
Brand: Springer-Verlag New York Inc.
SKU: 9781461351610
Price: 553.38 RON
Availability: InStock

CD13/Aminopeptidase N and CD26/Dipeptidylpeptidase IV in Medicine and Biology

Autor: Jürgen Langner, Siegfried Ansorge

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Editura: Springer-Verlag New York Inc.

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This book has a strong focus on the role APN and DPIV play in the hematopoietic system, where again...

Informații despre carte

Autor

Jürgen Langner, Siegfried Ansorge

Limbă

engleză

Legare

Carte - Carte broșată

Publicat

2012

Pagini

310

EAN

9781461351610

ISBN

1461351618

Enbook ID

02186912

Editura

Springer-Verlag New York Inc.

Greutate

504

Dimensiuni

155 x 17 x 18

Descriere completă

This book has a strong focus on the role APN and DPIV play in the hematopoietic system, where again signal peptides and small proteins (cytokines) are among the most interesting substrates. Additionally, both the membrane bound peptidases play roles as partners in signal transduction of lymphocytes and monocytes, and inhibition of their enzymatic activity results in cell cycle arrest, inhibition of DNA synthesis and characteristic changes of cytokine secretion pattern of T cells. This knowledge more and more is used as the base of therapeutic strategies in the treatment of a variety of inflammatory and autoimmune diseases as well as of tumors of different origin. The editors themselves with their colleagues have contributed important results about APN and DPIV that are reviewed here, and additionally, most of the leading groups in this field from Europe, U.S., Australia and Japan have contributed reviews and latest, partially unpublished results of their work.

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Ectopeptidases

CD13/Aminopeptidase N and CD26/Dipeptidylpeptidase IV in Medicine and Biology

Informații despre carte

Descriere completă

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