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Carte Cyclosporin A.W. Thomson

Cyclosporin

Mode of Action and Clinical Applications

Autor: A.W. Thomson
Limbă: engleză
Legare: Carte broșată
Editura: Springer
Disponibilitate: În depozitul extern
Expediem în 5-8 zile
275.89 lei
Cyclosporin has had a remarkable effect on clinical organ transplantation. Prior to its introduction...

Informații despre carte

Autor
A.W. Thomson
Limbă
engleză
Legare
Carte - Carte broșată
Publicat
2011
Pagini
384
EAN
9789401068741
ISBN
9401068747
Enbook ID
02184860
Editura
Springer
Greutate
593
Dimensiuni
155 x 235 x 21

Descriere completă

Cyclosporin has had a remarkable effect on clinical organ transplantation. Prior to its introduction, considerable advances had been made in the grafting of vital organs, particularly the kidney, heart and liver. In many developed countries, however, transplantation was not considered wo-rthwhile in terms of gain for the investment of resources. The improved results of kidney grafts following the use of cyclosporin has changed this attitude. For all types of organ transplantation, cyclosporin has resulted in an improvement of functional graft survival and has allowed a reduction in steroid dose and, in some cases, no steroids at all. It has permitted the first successful experimental transplantation of the heart and lungs in primate species by Reitz and colleagues and their results were applied directly to the clinic. It was largely due to the introduction of cyclosporin that the Washington Consensus Meeting on Liver Transplantation came to a favourable recommendation and the result has been the proliferation of units performing liver transplantation, approximately fifty in North America and another fifty in Europe, where previously there had been a handful. Having been involved in cyclosporin for organ grafting from the beginning, I have been able to witness these developments which have far exceeded my expectations once the nephrotoxicity of cyclosporin was demonstrated in man. It is fitting that Dr.

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