CpG Islands

Methods and Protocols

Autor: Miguel A. Peinado, Tanya Vavouri

Limbă:

Legare: Copertă tare

Editura: Humana Press Inc.

Disponibilitate: În depozitul extern

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This detailed volume examines bioinformatic and molecular biological methods useful to identify and...

Informații despre carte

Autor

Miguel A. Peinado, Tanya Vavouri

Limbă

engleză

Legare

Carte - Copertă tare

Publicat

2018

Pagini

340

EAN

9781493977673

ISBN

1493977679

Enbook ID

18730233

Editura

Humana Press Inc.

Greutate

893

Dimensiuni

178 x 254 x 25

Descriere completă

This detailed volume examines bioinformatic and molecular biological methods useful to identify and to explore the functions of CpG islands, key navigation points to understand gene regulation in fundamental processes such as development and cell differentiation as well as in diseases like cancer. Beginning with a historical perspective and important properties of CpG islands, the book continues with sections on computational and wet lab methods related to the study of DNA methylation, and in-depth protocols for the analysis of CpG island functional features including epigenetic profiling and chromatin interactions. Written for the highly successful Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and practical, CpG Islands: Methods and Protocols aims to provide readers with the information and methodologies necessary to continue to decipher how a genome's structure and organization contribute to regulate biological processes.

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CpG Islands

Methods and Protocols

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